KMID : 1189320130070030227
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Asian Spine Journal 2013 Volume.7 No. 3 p.227 ~ p.231
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Giant Invasive Sacral Schwannoma Showing Chromosomal Numerical Aberrations [-14,+18,+22]
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Kanamori Masahiko
Yasuda Taketoshi Hori Takeshi Suzuki Kayo
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Abstract
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Here, we report on a rare case of a giant invasive sacral schwannoma. The patient was a 58-year-old woman who had a 6-year history of non-specific buttock pain. Histological investigation confirmed the diagnosis of cellular schwannoma. The following numerical aberration was detected using the GTG-banding method for karyotypes: 47,XX,-14,+18,+22. Cytogenetic studies of schwannomas have indicated a complete or partial loss of chromosome 22 as the most common abnormality, but this case is cytogenetically rare because of the recurrence of trisomy 22.
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KEYWORD
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Sacrum, Neurilemmoma, Cytogenetics
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